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Spot - 21 Dec 2004 00:06 GMT

My ? is when can I safely begin to resume giving my dog Deramaxx after
stopping prednisone. He has been on prednisone for over month for a mast
cell tumor in his mouth. While the prednisone was working well to control
his arthritis along with the cancer it now is not due to the fact that the
vet has cut the dosage to 20 mg every other day. We started the every other
dose on Thursday and his arthritis is making him miserable now. I called
the vet today and she's out till tomorrow and the assistant didn't call me
back and he's in a lot of pain. He had his last dose 20 mg dose last night
at 6pm and I would love to be able to start him back on his Deramaxx ASAP
and to stop the pred at this point. I would rather he be comfortable than
be in this kind of misery.

I just don't know if 24 hours is long enough for this to be out of his
system so it doesn't cause any gastric problems or possible bleeding.

Thanks for any help
Celeste

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diddy - 21 Dec 2004 01:28 GMT

<NoSpamMe@verizon.net> whittled the following words:

> I just don't know if 24 hours is long enough for this to be out of his
> system so it doesn't cause any gastric problems or possible bleeding.

I had a dog with chronic gastric bleeding, and successfully kept him from
bleeding while on Deramaxx by putting him on Prilosec and carafate and
tagamet.
Carafate is prescription. Prilosec and tagamet is OTC. All three were
prescribed by specialists.

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Spot - 21 Dec 2004 02:16 GMT

Diddy,

Thanks for the reply I've already thought about the carafate since he seems
to have an upset stomach this week and the cimetadine isn't helping like it
was. I'm hoping that it's more pain related and once the pain is under
control he'll go back to his old chow hound self. A Barney with no appetite
is one sick puppy it's just not in his charater. We've had no problems with
bleeding in the past but I know that prednisone and Deramaxx together are a
NO NO because the two together can cause major problems. I hate that he is
in so much pain and I'm deathly afraid to give him any Deramaxx till I'm
sure the pred has had sufficient time to get out of his system. He already
take 100 mg of Cimetadine three times a day and lately I've been changing
his last nightly dose from Cimetadine to Ranitadine since it seems to settle
his stomach more.

From what I can find on prednisone in dogs that on an every other day dosing
that there is a time period of 12 to 36 hours where the adrenal gland has to
and work on it's own because by that time the prednisone has been used and
is out of his system. So going from that I'm hoping that noon tomorrow
would be ok to put him back on his Deramaxx. I'm calling the vets first
thing and letting them know I need an answer ASAP. They either have to give
me an alternative pain medication for his arthritis or I stop the pred and I
really hate to do that since the tumor in his mouth seems to be gone now but
I can't have him in this kind of pain.

Celeste

> <NoSpamMe@verizon.net> whittled the following words:
>
[quoted text clipped - 6 lines]
> Carafate is prescription. Prilosec and tagamet is OTC. All three were
> prescribed by specialists.

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Pet Forum / Miscellaneous / Animal Health / December 2004

Help from any vet or anyone who's been through this.