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Pet Forum / Miscellaneous / Animal Health / January 2005



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fever of unknown origin

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Margaret - 25 Jan 2005 23:47 GMT
Hi,
I am posting this for a friend so the information may be sketchy.  She has a
3 yr. old spayed Chow who spiked a fever of 104.  She took her to the vet
and they started IV fluids and did blood work.  24 hours later, the temp.
returned to normal.  Test results indicated platelet count was low and WBC
"a little high."  Autoimmune test was negative.  Urinalysis was neg.  Chest
xray was neg.
Spots that were shaved for blood work and IV now appear bruised. Antibiotics
have not been given since the exact source of infection has not been found.
Vet doesn't know what the problem is so is keeping her to monitor temp. and
if it goes up again will do some specialized test (I don't know what it is).
Does anybody have any thoughts about what could be wrong?
Appetite had been good up until temp went up. Activity level was slightly
depressed when temp was up.
Thank you.
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Margaret
"Dogs leave paw prints on our hearts"

buglady - 26 Jan 2005 11:11 GMT
spiked a fever of 104.  She took her to the vet
> and they started IV fluids and did blood work.  24 hours later, the temp.
> returned to normal.  Test results indicated platelet count was low and WBC
[quoted text clipped - 4 lines]
> Vet doesn't know what the problem is so is keeping her to monitor temp. and
> if it goes up again will do some specialized test (I don't know what it is).

.........did they run a full tick panel?  I'd suggest giving doxy now and
see if the dog improves.  Tick tests take a while to get back.  If it's tick
disease, there's no time to waste.

buglady
take out the dog before replying
Deborah, DVM - 26 Jan 2005 13:29 GMT
> spiked a fever of 104.  She took her to the vet
> > and they started IV fluids and did blood work.  24 hours later, the temp.
[quoted text clipped - 17 lines]
> buglady
> take out the dog before replying

I'd agree.  Low platelets, bruising, and high fever = tick borne disease
until proven otherwise in my book!  Doxycycline is cheap (the oral form
anyway), and sure won't hurt if it's not needed.  A bit of prednisone might
be worthwhile as well, in case it is something autoimmune -- tests aren't
always 100%.

Deborah, DVM
Margaret - 26 Jan 2005 13:56 GMT
> I'd agree.  Low platelets, bruising, and high fever = tick borne disease
> until proven otherwise in my book!  Doxycycline is cheap (the oral form
[quoted text clipped - 4 lines]
>
> Deborah, DVM

Thank you.  I will pass this info along to her.  I think tick borne disease
is on the list of things to rule out but I'm not sure what tests have been
done for that. My friend says there has never been a problem with ticks, but
deer ticks are so tiny I'm sure they could be missed.

Margaret
buglady - 27 Jan 2005 11:47 GMT
 A bit of prednisone might
> be worthwhile as well, in case it is something autoimmune -- tests aren't
> always 100%.

.......isn't pred contraindicated though for ehrlichia?  If it's tick
disease doxy should show improvement pretty fast.  Just out of curiosity do
you see much of it in the panhandle?

buglady
take out the dog before replying
sighthounds & siberians - 27 Jan 2005 13:26 GMT
>  A bit of prednisone might
>> be worthwhile as well, in case it is something autoimmune -- tests aren't
>> always 100%.
>
>.......isn't pred contraindicated though for ehrlichia?

Yes.

>  If it's tick
>disease doxy should show improvement pretty fast.

Not if it's babesia, and some cases of ehrlichiosis are refractory to
treatment with doxycycline.  

> Just out of curiosity do
>you see much of it in the panhandle?

My experience is taking track Greyhounds from the panhandle, and TBDs
are common in the panhandle.  In the entire state of Florida,
actually.  

Mustang Sally
Deborah, DVM - 27 Jan 2005 13:40 GMT
>   A bit of prednisone might
> > be worthwhile as well, in case it is something autoimmune -- tests aren't
[quoted text clipped - 3 lines]
> disease doxy should show improvement pretty fast.  Just out of curiosity do
> you see much of it in the panhandle?

I don't know about pred being contraindicated.  Honestly it didn't used to
be, to my knowledge, but it's been a long time since I've seen a clinical
case of ehrlichiosis.  Which should answer your second question -- no
surprisingly I don't see very much of it.  Honestly I've not seen a tick
borne disease in the 2 years I've been in private practice here.  I've
suspected it several times, but it's always turned out to be something
different.

Deborah, DVM
buglady - 28 Jan 2005 12:01 GMT
I don't see very much of it.  Honestly I've not seen a tick
> borne disease in the 2 years I've been in private practice here.  I've
> suspected it several times, but it's always turned out to be something
> different.

.......yeah, I've asked the vet here (central FL) and he hadn't seen much of
it either.  Though there's lots of people who only bring their dogs in to
die in the exam room.......  ;-(

buglady
take out the dog before replying
Margaret - 30 Jan 2005 04:30 GMT
> I'd agree.  Low platelets, bruising, and high fever = tick borne disease
> until proven otherwise in my book!  Doxycycline is cheap (the oral form
[quoted text clipped - 4 lines]
>
> Deborah, DVM

Doxycycline has been started.  I think 2 tests for tick disease were done
(or 1 test repeated) and one was borderline and one was negative.  She is
currently acting OK in terms of energy and appetite.  The plan is to try the
doxy for 3 weeks and if she tolerates it, use it for 6 weeks. Still no
official diagnosis.  Vet said he could refer them to a specialist but my
friend is going to hold off on that for now.

Margaret
buglady - 30 Jan 2005 21:31 GMT
> Doxycycline has been started.  I think 2 tests for tick disease were done
> (or 1 test repeated) and one was borderline and one was negative.  She is
> currently acting OK in terms of energy and appetite.  The plan is to try the
> doxy for 3 weeks and if she tolerates it, use it for 6 weeks. Still no
> official diagnosis.

.you might take a look at this page.  The dose of doxy is higher than normal
for ehrlichia and Lyme.  There's a lot of other info on tick disease here
also, plus a link to a list:
http://www.minden.com/nowhereelse/canine_tick_disease.htm

buglady
take out the dog before replying
 
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