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Pet Forum / Miscellaneous / Animal Health / November 2005diagnosis and treatment for my doberman
9 yrs old doberman, suddenly showed symptoms of sluggishness and one night wanted to urinate repeatedly and was very uncomfortable. Following this was put on a course of cifran. 3-4 days later blood test showed low Hemoglobin and high blood urea and creatinine. The first impresion was kidney damage and was given IV gencef for 4 days this was followeby a oral course of cifran 250 mg for 4 days. One injection erythropoietin (human recombinanat) has been given. The next blood report showed normal blood urea and creatinine, but low Hb and platlets and high TLC count. Post this the dog wa on a course of microdox DT- for 9 days. The next blood report shows hemolytic anemia. The hemoglobin has fallen further and TLC and Neutrophils are still high. Today she ahs been stated on Monocef IV. IV dextrose has been given on every second day. The urine report shows loss of albumin and RBC in the urine. There is complete loss of appetitie, refusal of food and water, no willing ness to move and lack of response, shivering . What can be the cause nad diagnosis and what should be the treatment >9 yrs old doberman, suddenly showed symptoms of sluggishness and one night >wanted to urinate repeatedly and was very uncomfortable. Following this [quoted text clipped - 14 lines] > >What can be the cause nad diagnosis and what should be the treatment Suggest abdominal ultrasound to rule out lesions on any organs. One of the greyhounds placed by my group recently had symptoms similar to this; he had histiocytic sarcoma. Sally Hennessey I don't know what most of those drugs are, am assuming antibiotics of some sort. Has an xray or ultrasound of the abdomen been done? I'd be very suspicious of some sort of cancer, like hemangiosarcoma. You could also be dealing with immune-mediated hemolytic anemia, would need to run tests like coomb's, ana, rf. Don't know where you are, but around here I'd also be suspicious of tick-borne disease, and would treat with doxycycline. Deborah, DVM >9 yrs old doberman, suddenly showed symptoms of sluggishness and one night > wanted to urinate repeatedly and was very uncomfortable. Following this [quoted text clipped - 14 lines] > > What can be the cause nad diagnosis and what should be the treatment Abdomen Ultrasound done- it shows that there is a encapsulated mass - 75x 75 mm on the right lobe of the liver, with complex echo. It indicates a mass or an abscsis. Not very sure. The left kidney shows hydronephrosis and calculi. there is mylena as she is loosing blood in the stool. She has been on a cource of doxycyclin orally for 9 days. Now she is on cephradine 500 mg intravenous the dog is in india and there is no provision to do a coombs test or protozoan tests. Sounds like you may be dealing with cancer. You'd need to biopsy the liver mass to know for sure. You can look for autoagglutination as an alternative to a Coombs test -- you mix a drop of blood with a drop of saline -- if it clumps then you know you have some sort of immune-mediated disease. Outside of doing that, I'd probably be giving some hefty doses of prednisone along with the antibiotics to see what kind of response you got. Sounds like a sick puppy and a tough case. Good luck. Deborah, DVM > Abdomen Ultrasound done- it shows that there is a encapsulated mass - 75x > 75 mm on the right lobe of the liver, with complex echo. It indicates a [quoted text clipped - 9 lines] > the dog is in india and there is no provision to do a coombs test or > protozoan tests. |
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