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Pet Forum / Miscellaneous / Animal Health / March 2008



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Bordetella

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Luca - 27 Mar 2008 22:13 GMT
How often should dogs receive this vaccination? My vet in NY says only
when/before boarding, but the vet in SC says routinely every year.
Does it depend on the climate?
Dale Atkin - 27 Mar 2008 22:20 GMT
I think it depends more on the expected interaction with other dogs.

The vaccine is 'good for a year' (what ever that means). If they aren't
likely to be exposed to it, then they don't need the shot.

Likely exposure is anywhere with a high density of dogs (like a boarding
kennel). I do my guys because we visit the dog park just about every single
day.

Also bear in mind that the bordetella vaccine isn't completely effective.
Sometimes they'll get it anyways, it just reduces the chances.

Dale

> How often should dogs receive this vaccination? My vet in NY says only
> when/before boarding, but the vet in SC says routinely every year.
> Does it depend on the climate?
Sandy, DVM - 28 Mar 2008 00:34 GMT
It really depends on the lifestyle, Luca. For dogs that regularly
interact with other dogs (dog parks, etc.) then we recommend annual
re-vaccination. The label on the vaccine recommends giving it annually,
but there are some studies which show the immunity may only last 6
months or so. Some boarding kennels require the vaccine every 6 months,
and we'll abide by that if that's where the clients are boarding their
dogs. In our practice, if a dog doesn't interact with other dogs much
and they don't board or get groomed, then we don't recommend the
vaccine. That said, it's even more important for those dogs to get the
vaccine (preferably the intranasal variety) within 2 weeks of going into
the kennel (and not less than 3-4 days), if boarding is required.

So, there's no easy pat answer, but there are lots of variables to
consider and discuss with your veterinarian.

Sandy, DVM

> How often should dogs receive this vaccination? My vet in NY says only
> when/before boarding, but the vet in SC says routinely every year.
> Does it depend on the climate?
Lee - 28 Mar 2008 03:51 GMT
I titer my dogs, but after the first few times discovered that at one
year, the bordetella numbers were consistently low, whereas the other
values were fine. So I went back to just immunizing for that rather than
wasting $ on the test. I tend to believe the ~6 months may be closer to
the truth there.

I do have them vac'd (intranasal, although my dogs find that disgusting,
LOL) for bordetella because they go to class & agility. But one vet also
 pointed out that if I ever had to board in a hurry, ie family/personal
emergency, and the dogs weren't vac'd for it, I'd have a hard time
getting in because the kennels all wanted it given ahead of time.

> It really depends on the lifestyle, Luca. For dogs that regularly
> interact with other dogs (dog parks, etc.) then we recommend annual
[quoted text clipped - 16 lines]
>> when/before boarding, but the vet in SC says routinely every year.
>> Does it depend on the climate?
Dale Atkin - 28 Mar 2008 04:02 GMT
> I do have them vac'd (intranasal, although my dogs find that disgusting,
> LOL) for bordetella because they go to class & agility.

Not quite sure why you go intranasal? I was under the impression that the
only advantage of intranasal was that it took effect faster. If you know in
advance (~2 weeks) then isn't the injectable easier on the dog? (I for one
wouldn't like someone shoving that stuff up my nose!)

Dale
buglady - 28 Mar 2008 15:00 GMT
> Not quite sure why you go intranasal? I was under the impression that the
> only advantage of intranasal was that it took effect faster.

Nope, other way round.

Abstract
Journal of the American Veterinary Medical Association
January 1, 2002, Vol. 220, No. 1, Pages 43-48
doi: 10.2460/javma.2002.220.43

Comparative efficacy of an injectable vaccine and an intranasal vaccine in
stimulating Bordetella bronchiseptica-reactive antibody responses in
seropositive dogs

John A. Ellis , DVM, PhD, DACVP, DACVM G. Steven Krakowka , DVM, PhD, DACVP
Arthur D. Dayton , PhD Carrie Konoby , BS
Department of Veterinary Microbiology, Western College of Veterinary
Medicine, University of Saskatchewan, Saskatoon, SK, Canada S7N 5B4. (Ellis,
Konoby); Department of Veterinary Biosciences, College of Veterinary
Medicine, The Ohio State University, Columbus, OH 43210. (Krakowka); Pfizer
Animal Health, 1 Pfizer Way, Lee's Summit, MO 64081-2998. (Dayton)

Objective—To compare antibody responses to intranasal and SC Bordetella
bronchiseptica vaccines in seropositive dogs.

Design—Randomized controlled study.

Animals—40 young adult Beagles vaccinated against B bronchiseptica.

Procedure—Dogs were randomly assigned to 1 of 4 groups (intranasal vaccine,
SC vaccine, intranasal and SC vaccines, no vaccine) and vaccinated on day 0.
Serum and salivary B bronchiseptica-reactive antibody responses were
measured on days 0 through 7, 10, 14, 21, and 28.

Results—Dogs that were vaccinated with the SC vaccine, alone or in
combination with the intranasal vaccine, had a significant increase in serum
concentration of B bronchiseptica-reactive IgG beginning on day 5 and
persisting through day 28. Dogs that were vaccinated with the intranasal
vaccine alone had a significant increase in serum concentration of B
bronchiseptica- reactive IgG beginning on day 10 and persisting through day
28, but serum IgG concentration in these dogs was significantly less than
concentration in dogs that received the SC vaccine. Neither vaccine had a
demonstrable effect on salivary concentrations of B bronchiseptica-reactive
IgA or IgG. On day 10, all vaccinated groups had significantly higher serum
IgA concentrations than did unvaccinated control dogs.

Conclusions and Clinical Relevance—Results suggest that the SC B
bronchiseptica vaccine may be used to stimulate antibody responses in
seropositive dogs. There was no apparent benefit to administering these
vaccines simultaneously. Intranasal vaccines may not be effective for
booster vaccination of dogs previously exposed to or immunized against B
bronchiseptica. Dogs should be vaccinated at least 5 days prior to exposure
to B bronchiseptica. (J Am Vet Med Assoc 2002;220:43–48)

If you know in
> advance (~2 weeks) then isn't the injectable easier on the dog? (I for one
> wouldn't like someone shoving that stuff up my nose!)
>
> Dale
Dale Atkin - 29 Mar 2008 05:31 GMT
>> Not quite sure why you go intranasal? I was under the impression that the
>> only advantage of intranasal was that it took effect faster.
>
> Nope, other way round.

Now that is *very* interesting. I've forwarded this to the vet clinic I'm at
to see what they have to say about it.  I was positive that they typically
go the other way around, but they don't use intranasal all that much, so I
could be mistaken.

Dale
buglady - 29 Mar 2008 12:33 GMT
> Now that is *very* interesting. I've forwarded this to the vet clinic I'm at
> to see what they have to say about it

........Before one can say anything, best to read the whole journal article.
If you check PubMed for this article there may be some others to read also.

buglady
take out the dog before replying
Lee - 29 Mar 2008 13:52 GMT
When I first started going to our regular vet, they used the intranasal.
Then switched to injectable. Within the next few (forget the number, but
not many) visits, they'd switched back to intranasal and said they'd
found it worked better, although I forget the exact problem/rationale
that prompted the change. I think it had something to do with an
increase in bordetella cases in their boarding area in dogs who'd rec'd
the IM/SC (whichever it is).

>>> Not quite sure why you go intranasal? I was under the impression that the
>>> only advantage of intranasal was that it took effect faster.
[quoted text clipped - 6 lines]
>
> Dale
Suja - 28 Mar 2008 21:17 GMT
"Sandy, DVM" <nospam@thisaddress.com> wrote in message:

> It really depends on the lifestyle, Luca. For dogs that regularly
> interact with other dogs (dog parks, etc.) then we recommend annual
> re-vaccination.

I have to say that I haven't really understood the point of this particular
vaccine.  It's efficacy is demonstrated to be only 6 months, it doesn't
provide any protection against some of the more common strains, and after
all, what is it that you're vaccinating against?  The doggie equivalent of a
cold?  A flu?

In kennel settings, it's understandable because of how contagious it is, but
I don't know how worried JQP should be.  In 7 years at the dog park (dogs
have had bordatella vaccine only when they've had to be boarded), we've had
one regular, whose dog had been vaccinated, come down with KC.  That's been
it.

Suja
Sandy, DVM - 29 Mar 2008 14:40 GMT
> "Sandy, DVM" <nospam@thisaddress.com> wrote in message:
>
[quoted text clipped - 9 lines]
> all, what is it that you're vaccinating against?  The doggie equivalent of a
> cold?  A flu?             [snip]
I think of it along the lines of the human flu vaccine. Many people get
the vaccine, but there are a couple of variables that make it worthwhile:
1) will you encounter anyone with the flu this season?
2) will that person be carrying 1 of the 2-4 strains that are in this
year's vaccine?

If someone has a slightly mutated strain of the flu, then you're likely
to get sick whether you had the vaccine or not. As an example, look at
this year's flu season. The case numbers were much higher than
anticipated and, IIRC, some fairly high number of patients had had the
vaccine. This was all because the virus had changed a bit from what was
expected. If your dog gets a Bordetella vaccine, then (s)he'll be less
likely to get that bacterial infection. If a dog at the dog park or the
boarding facility has some garden-variety upper respiratory virus, then
your dog is susceptible regardless whether (s)he got the vaccine. The
risk will always be there that your dog will get a contagious disease
when (s)he is in a group situation, vaccines just lessen the likelihood.

I would argue your assertion that "it doesn't provide any protection
against some of the more common strains." Bordetella is a common,
contagious organism in dogs (and cats). I'm not sure what other
"strains" the vaccine can protect against. The situation will never be
like it is in human medicine where the patients with respiratory
infections are cultured/analyzed/etc. and an exact known organism is
monitored for prevalence, then possibly included in some future
variation of the vaccine. There's just not enough money in this
situation for companies to do this for pets.

Sandy, DVM
diddy - 29 Mar 2008 14:45 GMT
>> "Sandy, DVM" <nospam@thisaddress.com> wrote in message:
>>
[quoted text clipped - 38 lines]
>
> Sandy, DVM

Bordatella can possibly be career ending to Scenting (hunting, tracking,
SAR, Narcotics, Explosives) dogs. Therefore the conversations in those
interest groups constantly drift to, vaccinate and accept time off post
vaccine, take the risk of not vaccinating, vaccinate and risk potential
nose scarring. I vaccinate every 6 months
 
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