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Pet Forum / Miscellaneous / Animal Health / January 2004



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discoid lupus

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John/Lisa - 26 Jan 2004 17:23 GMT
a few months ago my 8 year old sheltie/whippet female was diagnosed with
discoid  lupus.  I think she had signs of it years ago, but we thought it
was staff infection caused by fleas and did eventually clear up with
antibiotics (probably would have cleared on it's own.)  During the time
before her official diagnosis we did try prednazone, and for that reason I'm
reluctant to try it again  (she was a sad looking pooch)  I have given her
Vitamin E and omegas (trying to make the skin happy)  it appeared to not
make a difference, so I stopped that was a while ago.  Now I can see it
coming back.  Her tummy has been fine for quite awhile, but it's her
nostrils and the fuzzy area between her nose and mouth.  One side had a
small sore, it now is a pale spot in a dark area.  Yesterday I noticed a
sore area on the other side.  her nostrils are also affected.
Another thing about her is that she is an extremely sensitive dog.  She has
episode of shaking.  she is sound sensitive, but the shaking sometimes looks
like seizures.  (I think she's a stressed out dog sometimes, yet there are
times she is a true couch potato)

What I am asking, is in your opinion what could be possible triggers.

We also tried hypo allegettic food it made no difference.
The diagnosis was made by a biopsy

Thanking you in advance, Lisa and Trixie
doe - 26 Jan 2004 17:36 GMT
>Subject: discoid lupus
>From: "John/Lisa" jdance@shaw.ca
[quoted text clipped - 24 lines]
>
>Thanking you in advance, Lisa and Trixie

The fact the makers of dog food have no idea how much iron they are putting in
the food leads to oxidative stress which leads to lupus ..

Hemosiderosis is iron deposits and as evidenced in this article .. running
rampant through the canine community.

J S Afr Vet Assoc 1999 Dec;70(4):158-60   Renal pathology in working dogs in
the South African National Defence Force.    Short RP, Lobetti RG, Nesbit JW
  South African Military Health Service Headquarters, Centurion.      Urine
analysis, serum biochemical profile and a cortical wedge biopsy   for
histopathological examination was performed on 42 South African   National
Defence Force (SANDF) dogs from around the country. The only   significant
finding on urine analysis and serum biochemistry was a   relatively large
number (16/42) of dogs with elevated serum inorganic   phosphate levels
Histopathology revealed that only 9 of the animals   had normal kidneys
reflected in the wedge biopsy material, with over   50% of them showing
signs
of glomerular pathology (primarily   mesangioproliferative
glomerulonephritis).
Other conditions detected   histopathologically were haemosiderosis (47% of
animals), focal   nephrosis (2.4%), membranoproliferative glomerulonephritis
(2.4%),   focal interstitial nephritis (4.7%) and acute tubular nephrosis
(4.7%). The lesions observed were of limited distribution and extent;   this
histopathological finding may account for the absence of   significant
abnormalities on urine analysis or serum biochemistry   profiles. It appears
from these results that a large percentage of the   SANDF population would
be
expected to have mild renal lesions, but   that these lesions are not severe
enough to lead to clinical signs.   The findings of this study are similar
to
those of randomly selected   populations of non-military dogs performed in
other areas of the   world, which also demonstrated an unexpectedly high
incidence of   histopathological renal pathology in dogs considered healthy.
These   lesions may well, however, play a role in later life, and it is
recommended that military veterinarians maintain an index of suspicion   for
renal disease, particularly glomerular disease. The aetiology of   the
histopathological lesions is unknown.      PMID: 10855840, UI:

Who loves ya.
Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore
DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking
John/Lisa - 26 Jan 2004 18:05 GMT
Thank you for answering so quickly
In town here there is a shop that makes natural pet food. I will drop in and
see what  they have to say and sell.

thanks again, Lisa and Trixie

> >Subject: discoid lupus
> >From: "John/Lisa" jdance@shaw.ca
[quoted text clipped - 68 lines]
> Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore
> DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking
 
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